Methotrimeprazine

(meth oh trye MEP ra zeen)

What key warnings do I need to know about before giving this drug to my child?

• Sometimes drugs are not safe when your child takes them with other drugs. They can cause bad side effects. This is one of those drugs. Be sure to talk to your child’s doctor about all the drugs your child takes.

Is it safe for my child to take this drug?

• Not if your child has an allergy to methotrimeprazine, phenothiazines, or any other part of this drug.
• Be sure to let the doctor know if your child has any allergies or side effects to drugs, foods, or dyes. Make sure to tell about the allergy and what signs your child had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
• Not if your child has any of these health problems: Bleeding problems or liver disease.

Why does my child need this drug?

• It is used to treat schizophrenia. It may take 6 weeks to see the full effect.
• It is used to ease pain.
• It is used to treat problems with how one acts.
• It is used to treat sleep problems.
• It is used to treat upset stomach and throwing up.

How does this drug work?

• Methotrimeprazine lowers the feeling of pain and how one reacts to pain.
• It affects the throwing up (vomiting) center in the brain.
• It calms the brain.

How is this drug given?

• Oral:
• Give this drug with meals.
• Keep a pain diary.
• Shot:
• It is given as a shot into a muscle.

How long does this drug take to work?

• Your child may start feeling better soon after starting this drug.
• If treating schizophrenia, it may take 6 weeks to see the full effect.

What do I do if my child misses a dose? (does not apply to patients in the hospital)

• Give a missed dose as soon as you think about it.
• If it is close to the time for your child's next dose, skip the missed dose and go back to your child's normal time.
• Do not give 2 doses or extra doses.

What safety measures do I need to take when my child is using this drug?

• Keep a list of all your child's drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your child's doctor.
• If you have high blood sugar (diabetes), talk with your doctor.
• If your child has heart disease, talk with the doctor.
• If your child has seizures, talk with the doctor.
• Check all drugs your child is taking with your child's doctor. This drug may not mix well with some other drugs.
• Avoid giving your child other drugs and natural products that may slow your child's actions.
• This drug may cause your child to be less alert. Have your child avoid tasks or actions that call for alertness. These include playing (for example, riding a bicycle, rollerblading, sports) or using items that call for your child to have focus or coordination (for example, scissors, lawnmower, electric scooters, or toy cars). Your child's actions will be closely watched until you see how this drug affects him/her. School work may be hard for your child to focus on and get done.
• Limit your child's use of caffeine and chocolate. Use with this drug may cause nervousness, shakiness, and a fast heartbeat.
• Be careful in hot weather. Have your child drink lots of fluids to stop fluid loss.

What are some side effects of this drug?

• Feeling lightheaded, sleepy, having blurred eyesight, or a change in thinking clearly. Have your child avoid tasks or actions that call for him/her to be alert or have clear eyesight until you see how this drug works.
• Feeling dizzy. Have your child get up slowly over a few minutes when sitting or lying down. Have your child be extra careful climbing stairs.
• Headache.
• Upset stomach or throwing up. Many small meals and good mouth care may help. Older children may suck hard, sugar-free candy.
• Hard stools (constipation). Drinking more liquids, working out, or adding fiber to your diet may help. Talk with your doctor about a stool softener or laxative.
• Dry mouth. Good mouth care may help. Older children may suck hard, sugar-free candy. Have your child see a dentist often.
• Weight gain.

When do I need to call my child's doctor?

• If any of this news causes you to be worried, any of the unwanted side effects happen, or if your child is not better after taking this drug.
• If you think there was an overdose, call your local poison control center or ER right away.
• If your child shows signs of a very bad reaction, call your child's doctor or the ER right away. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; swelling of face, lips, tongue, or throat; or if your child is not acting normal.
• If your child shows signs of very bad dizziness or passes out.
• If your child has a fast heartbeat.
• If your child has trouble breathing.
• If your child shows signs of low mood (depression), thoughts of killing him/herself, nervousness, emotional ups and downs, thinking that is not normal, anxiety, or lack of interest in life.
• If your child has a change in thinking clearly and with logic.
• If your child has shakiness, trouble moving around, or stiffness.
• If your child has poor pain control.
• If your child has a very bad upset stomach or is throwing up.
• If your child has very hard stools (constipation).
• If your child is not able to pass urine.
• If your child has any bruising or bleeding.
• If your child has dark urine or yellow skin or eyes.
• If your child is feeling very tired or weak.
• If your child gets a rash.
• If your child’s health problem does not get better or if you believe your child’s health problem is worse.

How do I store and/or throw out this drug?

• Store at room temperature.
• Protect tablets from water. Do not store in a bathroom or kitchen.
• Shot:
• This drug will be given to your child in a hospital or doctor's office. You will not store it at home.

General drug facts

• If your child has a very bad allergy, he/she needs to wear an allergy ID at all times.
• You may get this drug by drug order only. If there are refills, call your pharmacy. If your child does not have refills left, you may need to call your child's doctor.
• Get rid of this drug when your child no longer needs it or if the drug is outdated.
• Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
• In Canada, take any unused drugs to the pharmacy. Also, visit http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th to learn about the right way to get rid of unused drugs.http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th to learn about the right way to get rid of unused drugs.
• Do not share your child's drug with others and do not give anyone else's drug to your child.
• Keep all drugs out of the reach of children and pets.
• Keep a list of all your child's drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your child's doctor.
• Call your doctor for help with any side effects. If in the U.S., you may also call the FDA at 1-800-FDA-1088 or if in Canada, you may also call Health Canada's Vigilance Program at 1-866-234-2345.
• Talk with the doctor before giving your child any new drug, including OTC, natural products, or vitamins.
• If you do not use a drug the right way, it may not be safe. Follow what your child’s doctor tells you.

Copyright © 1978- Lexi-Comp Inc., The Children's Hospital, Denver, CO., and Pediatric Pharmacy Advocacy Group, Inc. All Rights Reserved. This information is protected under US and international copyright law. Unauthorized use or reproduction is prohibited.