Do kids have a natural immunity to fifth disease once they've had the virus?
- Lenore

Usually, kids who've been infected with the virus that causes fifth disease (parvovirus B19) become immune to it and won't become infected again.

Fifth disease is one of the most common and contagious childhood illnesses. Fortunately, fifth disease usually doesn't make a child very ill. A "slapped-cheek" rash on the face that spreads to the body following mild, cold-like symptoms (like a fever and runny nose) usually are the only symptoms. But fifth disease can be dangerous to pregnant women and people with certain medical conditions.

The best way to avoid infections like fifth disease is to encourage frequent hand washing.

Reviewed by: Larissa Hirsch, MD
Date reviewed: April 2012

Have a question? Email us.

Although we can't reply personally, you may see your question posted to this page in the future. If you're looking for medical advice, a diagnosis, or treatment, consult your doctor or other qualified medical professional. If this is an emergency, contact emergency services in your area.

Note: Clicking these links will take you to a site outside of KidsHealth's control.